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Answer for the clue "Brain surgery on human patients intended to relieve severe and otherwise intractable mental or behavioral problems ", 13 letters:
psychosurgery

Word definitions for psychosurgery in dictionaries

Wiktionary Word definitions in Wiktionary
n. (context surgery English) Surgery of the brain to treat or alleviate mental illness.

Wikipedia Word definitions in Wikipedia
Psychosurgery , also called neurosurgery for mental disorder ( NMD ), is the neurosurgical treatment of mental disorder . Psychosurgery has always been a controversial medical field. The modern history of psychosurgery begins in the 1880s under the Swiss ...

WordNet Word definitions in WordNet
n. brain surgery on human patients intended to relieve severe and otherwise intractable mental or behavioral problems

Usage examples of psychosurgery.

He used combinations of psychosurgery, behavioral modification, and potent neurotropics, as well as old-fashioned torture.