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Answer for the clue "Any severe mental disorder in which contact with reality is lost or highly distorted ", 9 letters:
psychosis

Word definitions for psychosis in dictionaries

Douglas Harper's Etymology Dictionary Word definitions in Douglas Harper's Etymology Dictionary
1847, "mental derangement," Modern Latin, from Greek psykhe- "mind" (see psyche ) + -osis "abnormal condition." Greek psykhosis meant "a giving of life; animation; principle of life."

Wikipedia Word definitions in Wikipedia
Psychosis is a generic psychiatric term for a mental state characterized by loss of contact with reality. Psychosis or psychotic may also refer to: Brief psychotic disorder , The Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text ...

WordNet Word definitions in WordNet
n. any severe mental disorder in which contact with reality is lost or highly distorted [also: psychoses (pl)]

Longman Dictionary of Contemporary English Word definitions in Longman Dictionary of Contemporary English
noun COLLOCATIONS FROM CORPUS ■ ADJECTIVE affective ▪ Medcalf goes even further, quoting a clinician's opinion that Hoccleve suffered several episodes of a manic form of affective psychosis . ▪ Over 70 percent of both groups were considered psychotic, with ...

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Psychosis \Psy*cho"sis\, n. [NL. See Psycho- .] Any vital action or activity. --Mivart. (Med.) A disease of the mind; especially, a functional mental disorder, that is, one unattended with evident organic changes.

Wiktionary Word definitions in Wiktionary
n. (label en psychology) A severe mental disorder, sometimes with physical damage to the brain, marked by a deranged personality and a distorted view of reality.

Usage examples of psychosis.

To expose oneself to an archetypical entity was an invitation to be absorbed into it, all conscious identity lost in irreducible psychosis.

All the same I found some books on neuroses and psychoses which made me think.

Out there, they had faced, and been distorted by, their own inner demons, their own fears and frustrations and neuroses and psychoses, but this irrationality gave them great power.

In my college psychology class we briefly studied neurosis and psychosis, and I wondered which of the two I might be experiencing.

This is due to a determined hypothesis that the later stage of the ongoing disease of this Pandemic is that of psychosis simulating in otherwise normal people, that of schizophrenia, paranoia, perhaps violent episodes.

The reintegration of her personality was surely complete by now, but if she had gone completely around the bend into full-blown psychosis, he did not want to risk his own sanity by reading her mind.

This process is equally striking in individual psychosis and in group-dependent psychosis, where traditional forms of moral behavior cease to function in relation to the scapegoat group.

In prescribing this drug, physicians are warned that Ritalin is contraindicated for patients with psychological problems such as depression, psychosis, or chronic fatigue.

Wolf gene pack dynamics, serotonin shutout and Envoy psychosis to pilot the whole fucking shambles.

After this transference of psychoses the victims would be relieved, and the obsessing spirits could then be reached by the advanced spirits, who would care for them and instruct them regarding the higher laws of life.

Electrical discharges in the limbic system sometimes result in symptoms similar to those of psychoses or those produced by psychedelic or hallucinogenic drugs.

That they do not have reactive psychoses and do not suffer from psychotic microepisodes under stress.

Actually, there is a whole sub-field in psychodynamic theories of narcissism, which tries to explain the dynamics of reactive psychoses in pathological narcissism.

Soon he knew about the many forms of schizophrenia, as well as other psychoses, neuroses, paranoias, and an entire alphabet of phobias.

When you took a child like that during the sixties and you added marijuana, it sowed the seeds of the psychosis that most of these radicals are clearly exhibiting today.