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Answer for the clue "A disorder characterized by an abnormal increase in the number of red blood cells in the blood ", 12 letters:
polycythemia

Word definitions for polycythemia in dictionaries

WordNet Word definitions in WordNet
n. a disorder characterized by an abnormal increase in the number of red blood cells in the blood

Wiktionary Word definitions in Wiktionary
alt. (context disease English) A rare disorder in which the bone marrow produces an abnormally large amount of blood cells, often red blood cells. n. (context disease English) A rare disorder in which the bone marrow produces an abnormally large amount ...

Wikipedia Word definitions in Wikipedia
Polycythemia (also known as polycythaemia or polyglobulia ) is a disease state in which the proportion of blood volume that is occupied by red blood cells increases. Blood volume proportions can be measured as hematocrit level. A hematocrit of >55% is seen ...

Usage examples of polycythemia.

Cora showed a slight discoloration from central cyanosis due to polycythemia and reduced oxygen saturation, despite the genetically modified hemoglobin-Y and the enhanced lung capacity.

In the next two hours, Honey diagnosed a rare case of Reiter's syndrome, osteitis deformans polycythemia, and malaria.

In the next two hours, Honey diagnosed a rare case of Reiter's syn­drome, osteitis deformans polycythemia, and malaria.