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Answer for the clue "Lack of the enzyme needed to turn phenylalanine into tyrosine results in an accumulation of phenylalanine in the body fluids which causes various degrees of mental deficiency ", 3 letters:
pku

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Wikipedia Word definitions in Wikipedia
PKU can refer to: Phenylketonuria , a genetic disease Peking University , Beijing, China Pku , an Armenian musical instrument Sultan Syarif Kasim II International Airport , Pekanbaru, Riau, Indonesia, IATA code