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Answer for the clue "An abnormal tightness of the foreskin preventing retraction over the glans ", 8 letters:
phimosis

Word definitions for phimosis in dictionaries

WordNet Word definitions in WordNet
n. an abnormal tightness of the foreskin preventing retraction over the glans

Wikipedia Word definitions in Wikipedia
Phimosis is a condition of the penis where the foreskin cannot be fully retracted over the glans penis . The term may also refer to clitoral phimosis in women, whereby the clitoral hood cannot be retracted, limiting exposure of the glans clitoridis . At ...

Douglas Harper's Etymology Dictionary Word definitions in Douglas Harper's Etymology Dictionary
1670s, from Greek phimosis , literally "muzzling," from phimos "a muzzle."

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Phimosis \Phi*mo"sis\, n. [NL., fr. Gr. ? a muzzling, fr. ? muzzle.] (Med.) A condition of the penis in which the prepuce can not be drawn back so as to uncover the glans penis.

Wiktionary Word definitions in Wiktionary
n. (context medicine English) A contraction of the foreskin (either as a stage of development or a pathological condition), which prevents it from being retracted.

Usage examples of phimosis.

The incomplete or irregular development is more frequent, but most common is excessive development of the prepuce, constituting phimosis, when there is abnormal adherence with the glans.