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Answer for the clue "Grave harmfulness or deadliness ", 14 letters:
perniciousness

Word definitions for perniciousness in dictionaries

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Pernicious \Per*ni"cious\, a. [L. perniciosus, from pernicies destruction, from pernecare to kill or slay outright; per + necare to kill, slay: cf. F. pernicieux. Cf. Nuisance , Necromancy .] Having the quality of injuring or killing; destructive; very ...

WordNet Word definitions in WordNet
n. grave harmfulness or deadliness [syn: toxicity ]

Wiktionary Word definitions in Wiktionary
n. The condition of being pernicious; destructiveness

Usage examples of perniciousness.

The utter perniciousness of romantic love couldn't be more obvious in his case.

They forgot the perniciousness of habit—of the habit of having decisions made for you.