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Answer for the clue "A disease caused by deficiency of niacin or tryptophan (or by a defect in the metabolic conversion of tryptophan to niacin) ", 8 letters:
pellagra

Alternative clues for the word pellagra

Word definitions for pellagra in dictionaries

Douglas Harper's Etymology Dictionary Word definitions in Douglas Harper's Etymology Dictionary
chronic disease caused by dietary deficiency and characterized by skin eruptions, 1811, a hybrid formed from Latin pellis "skin" (see film (n.)) + Greek agra "a catching, seizure," related to agrein "to take, seize." But OED suggests it might be originally ...

Wiktionary Word definitions in Wiktionary
n. (context pathology English) A disease, with skin lesions and mental confusion, primarily caused by a niacin deficiency.

Longman Dictionary of Contemporary English Word definitions in Longman Dictionary of Contemporary English
noun EXAMPLES FROM CORPUS ▪ Another form of mental disorder, pellagra , was associated clinically with diarrhoea and dermatitis. ▪ Colitis, which is histologically similar to ulcerative colitis, has also been described in association with pellagra . ▪ Eat ...

WordNet Word definitions in WordNet
n. a disease caused by deficiency of niacin or tryptophan (or by a defect in the metabolic conversion of tryptophan to niacin); characterized by gastrointestinal disturbances and erythema and nervous or mental disorders; may be caused by malnutrition or ...

Usage examples of pellagra.

Their absence is probably responsible for certain diseases, such as beriberi, scurvy, and possibly pellagra, as well as much ill health of a less definite sort.

The granaries were full and the children of the poor grew up rachitic, and the pustules of pellagra swelled on their sides.