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Answer for the clue "The origination and development of a disease ", 12 letters:
pathogenesis

Word definitions for pathogenesis in dictionaries

Wikipedia Word definitions in Wikipedia
The pathogenesis of a disease is the biological mechanism (or mechanisms) that lead to the diseased state. The term can also describe the origin and development of the disease, and whether it is acute , chronic , or recurrent . The word comes from the Greek ...

Douglas Harper's Etymology Dictionary Word definitions in Douglas Harper's Etymology Dictionary
1876, from patho- + genesis .

Wiktionary Word definitions in Wiktionary
n. 1 The origin and development of a disease. 2 The mechanism whereby something causes a disease.

WordNet Word definitions in WordNet
n. the origination and development of a disease

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Pathogenesis \Path`o*gen"e*sis\, n. (Med.) Pathogeny.

Usage examples of pathogenesis.

Psychological stress perturbs epidermal permeability barrier homeostasis: Implications for the pathogenesis of stress-associated skin disorders.

Patter son with the following words--xenopolycythemia, hematology, pathogenesis, disease.

That gave you that sense of being in contact with your inner self and loving the world and all, entactogenesis and em pathogenesis Bobby called them.