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Answer for the clue "Partial sterilization of foods at a temperature that destroys harmful microorganisms without major changes in the chemistry of the food ", 14 letters:
pasteurization

Word definitions for pasteurization in dictionaries

Douglas Harper's Etymology Dictionary Word definitions in Douglas Harper's Etymology Dictionary
1885, from pasteurize + -ation .

Wiktionary Word definitions in Wiktionary
n. (alternative spelling of pasteurisation English)

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Pasteurization \Pas*teur`i*za"tion\, n. A process devised by Pasteur for preventing or checking fermentation in fluids, such as wines, milk, etc., by exposure to a temperature of 140[deg] F., thus destroying the vitality of the contained germs or ferments. ...

Wikipedia Word definitions in Wikipedia
Pasteurization or pasteurisation is a process that kills microbes (mainly bacteria ) in food and drink , such as milk , juice , canned food , and others. It was invented by French scientist Louis Pasteur during the nineteenth century. In 1864 Pasteur discovered ...

WordNet Word definitions in WordNet
n. partial sterilization of foods at a temperature that destroys harmful microorganisms without major changes in the chemistry of the food [syn: pasteurisation ]

Usage examples of pasteurization.

My opinion - and it's an opinion of course, based on experience - is only to focus on the chemical compounds that are beneficial, but those could be artificial (even refined - Pasteurization is refinement for example) as well.