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Answer for the clue "A degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination ", 12 letters:
parkinsonism

Word definitions for parkinsonism in dictionaries

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Palsy \Pal"sy\, n.; pl. Palsies . [OE. palesie, parlesy, OF. paralesie, F. paralysie, L. paralysis. See Paralysis .] (Med.) Paralysis, complete or partial. See Paralysis . ``One sick of the palsy.'' --Mark ii. 3. Bell's palsy , paralysis ...

Wiktionary Word definitions in Wiktionary
alt. (context neurology disease English) A neurological syndrome characterized by tremor, hypokinesia, rigidity, and postural instability; a condition with the symptoms of Parkinson's disease, regardless of its cause. n. (context neurology disease English) ...

Wikipedia Word definitions in Wikipedia
Parkinsonism is a clinical syndrome characterized by tremor , bradykinesia , rigidity , and postural instability . Parkinsonism shares symptoms found in Parkinson's disease , from which it is named; but parkinsonism is a symptom complex, and differs from ...

Usage examples of parkinsonism.

And there are, of course, other examples: the treatment of endocrinologic disorders with appropriate hormones, the prevention of hemolytic disease of the newborn, the treatment and prevention of various nutritional disorders, and perhaps just around the corner the management of Parkinsonism and sickle-cell anemia.

L-Dopa produced, at first, a dramatic release from her Parkinsonism and oculogyric en-trancement, allowing almost normal speech and movement.

Skardon had aged twenty years, gained a dignified limp, eyes bleared with very dilute vinegar and the slight tremor of the hands signaling approaching parkinsonism.

Then the same thing took place in malignant hypertension, in Parkinsonism and other failures of the central nervous system, in muscular dystrophy, and so on, and so on.