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Answer for the clue "Characterized by pain and swelling ", 8 letters:
orchitis

Alternative clues for the word orchitis

Word definitions for orchitis in dictionaries

Wiktionary Word definitions in Wiktionary
n. (context medicine English) A painful inflammation of one or both testes.

Wikipedia Word definitions in Wikipedia
Orchitis or orchiditis (from the Ancient Greek ὄρχις meaning "testicle"; same root as orchid ) is inflammation of the testes . It can also involve swelling, heavy pains and frequent infection, and is more rarely known as didymitis (as in epididymis ).

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Orchitis \Or*chi"tis\, n. [NL., fr. Gr. ? a testicle + -itis.] (Med.) Inflammation of the testicles.

WordNet Word definitions in WordNet
n. inflammation of one or both testes; characterized by pain and swelling

Usage examples of orchitis.

He asserted that Vitamin C in such large doses helps with the treatment of hepatitis, mumps, measles, polio, viral pneumonia, viral orchitis, herpes, and influenza.