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Answer for the clue "A disease affecting the kidneys ", 11 letters:
nephropathy

Word definitions for nephropathy in dictionaries

WordNet Word definitions in WordNet
n. a disease affecting the kidneys [syn: kidney disease , renal disorder , nephrosis ]

Wiktionary Word definitions in Wiktionary
n. (context pathology English) Damage to, disease of, or abnormality of the kidneys.