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Answer for the clue "An abnormally small head and underdeveloped brain ", 12 letters:
microcephaly

Word definitions for microcephaly in dictionaries

Wikipedia Word definitions in Wikipedia
Microcephaly is a medical condition in which the brain does not develop properly resulting in a smaller than normal head . Microcephaly may be present at birth or it may develop in the first few years of life. Often people with the disorder have an intellectual ...

WordNet Word definitions in WordNet
n. an abnormally small head and underdeveloped brain [syn: microcephalus , nanocephaly ]

Wiktionary Word definitions in Wiktionary
n. A neurological disorder in which the person affected has an abnormally small head due to a failure of brain growth.

Usage examples of microcephaly.

The committee charged with carrying out the program issued instructions to all Reich health agencies to register children born with congenital deformities, including idiocy, Mongolism, microcephaly, hydrocephaly, missing limbs, malformation of the head, spina bifida, muscular dystrophy, mental retardation, and other congenital diseases.