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Answer for the clue "Antihistamine used to treat allergic responses (as rhinitis or dermatitis or pruritus) ", 13 letters:
methapyrilene

Word definitions for methapyrilene in dictionaries

WordNet Word definitions in WordNet
n. antihistamine used to treat allergic responses (as rhinitis or dermatitis or pruritus)

Wikipedia Word definitions in Wikipedia
"Thionylan" redirects here. The thionyl halides should not be confused with "thionylan" and include thionyl fluoride , thionyl chloride , and thionyl bromide . Methapyrilene is an antihistamine and anticholinergic of the pyridine chemical class which was ...

Wiktionary Word definitions in Wiktionary
n. A pyridine antihistamine drug with relatively strong sedative effects.