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Answer for the clue "Antihistamine used to treat allergic responses (as rhinitis or dermatitis or pruritus) ", 13 letters:
methapyrilene

Word definitions for methapyrilene in dictionaries

Wikipedia Word definitions in Wikipedia
"Thionylan" redirects here. The thionyl halides should not be confused with "thionylan" and include thionyl fluoride , thionyl chloride , and thionyl bromide . Methapyrilene is an antihistamine and anticholinergic of the pyridine chemical class which was ...

Wiktionary Word definitions in Wiktionary
n. A pyridine antihistamine drug with relatively strong sedative effects.

WordNet Word definitions in WordNet
n. antihistamine used to treat allergic responses (as rhinitis or dermatitis or pruritus)