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Answer for the clue "A disease caused by deficiency of niacin or tryptophan (or by a defect in the metabolic conversion of tryptophan to niacin) ", 8 letters:
mayidism

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n. a disease caused by deficiency of niacin or tryptophan (or by a defect in the metabolic conversion of tryptophan to niacin); characterized by gastrointestinal disturbances and erythema and nervous or mental disorders; may be caused by malnutrition or ...