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Answer for the clue "Relevance requiring careful consideration ", 11 letters:
materiality

Alternative clues for the word materiality

Word definitions for materiality in dictionaries

Douglas Harper's Etymology Dictionary Word definitions in Douglas Harper's Etymology Dictionary
1520s, "that which is the matter of something," from Modern Latin materialitas , from materialis (see material (adj.)). From 1560s as "quality of being material;" 1640s as "quality of being important to matters at hand."

Wikipedia Word definitions in Wikipedia
Materiality in architecture is the concept of, or applied use of, various materials or substances in the medium of building. Material is a relative term in architectural design and so may be used to designate materials which are considered to be virtual ...

Wiktionary Word definitions in Wiktionary
n. 1 The quality of being material; having a physical existence. 2 (context legal English) The quality of being of consequence to a legal decision.

WordNet Word definitions in WordNet
n. relevance requiring careful consideration [ant: immateriality ] the quality of being physical; consisting of matter [syn: physicalness , corporeality ] [ant: immateriality , immateriality ]

Usage examples of materiality.

For the strict materiality of the fire of hell we might adduce volumes of authorities from nearly every province of the Church.

Every juridical system is in some way a crystallization of a specific set of values, because ethics is part of the materiality of every juridical foundation, but Empire-and in particular the Roman tradition of imperial right-is peculiar in that it pushes the coincidence and universality of the ethical and the juridical to the extreme: in Empire there is peace, in Empire there is the guarantee of justice for all peoples.

Both actions are exertions of power that turn out to involve a sullying Fall into materiality, or more precisely into the abject, addictive dependencies of the flesh.