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Answer for the clue "A long-acting barbiturate used as a sedative ", 7 letters:
luminal

Word definitions for luminal in dictionaries

Douglas Harper's Etymology Dictionary Word definitions in Douglas Harper's Etymology Dictionary
"of or pertaining to a lumen ," 1897, with -al (1).

Wikipedia Word definitions in Wikipedia
Luminal may refer to: A trade name for the anti-epileptic drug phenobarbital Luminal (film) , a 2004 film by Italian director Andrea Vecchiato starring Denis Lavant "Luminal", a 2004 album by Sounds from the Ground In biology, pertaining to the lumen , ...

Wiktionary Word definitions in Wiktionary
a. (context biology English) of or pertaining to the lumen n. (context medicine English) A sedative.

Usage examples of luminal.

It had, after all, a luminal computer with a quarter the power of DEUS!

Because his senses were attuned to energy fluctuations—such as those made by shrouded Jem’Hadar—he remained keenly aware of the twenty or so luminal demihumans who milled about the restaurant and dance floor of Vic Fontaine’s lounge.