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Answer for the clue "A long-acting barbiturate used as a sedative ", 7 letters:
luminal

Word definitions for luminal in dictionaries

Wikipedia Word definitions in Wikipedia
Luminal is the debut film from Italian director Andrea Vecchiato . Named after the drug phenobarbitone , the film is based on the cult novel by Italian writer Isabella Santacroce . Santacroce's third novel, published in 2001, tells the story of teenagers ...

Wiktionary Word definitions in Wiktionary
a. (context biology English) of or pertaining to the lumen n. (context medicine English) A sedative.

Douglas Harper's Etymology Dictionary Word definitions in Douglas Harper's Etymology Dictionary
"of or pertaining to a lumen ," 1897, with -al (1).

Usage examples of luminal.

It had, after all, a luminal computer with a quarter the power of DEUS!

Because his senses were attuned to energy fluctuations—such as those made by shrouded Jem’Hadar—he remained keenly aware of the twenty or so luminal demihumans who milled about the restaurant and dance floor of Vic Fontaine’s lounge.