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Answer for the clue "Two species of small cacti of northeastern Mexico and southwestern United States having rounded stems covered with jointed tubercles mescal ", 10 letters:
lophophora

Word definitions for lophophora in dictionaries

Wikipedia Word definitions in Wikipedia
Lophophora is a genus of spineless, button-like cacti native to the southwestern United States ( Texas and New Mexico ) through Northeast Mexico and South to Querétaro in central Mexico. The species are extremely slow growing, sometimes taking up to thirty ...