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Answer for the clue "A skin condition marked by an overgrowth of layers of horny skin ", 9 letters:
keratosis

Word definitions for keratosis in dictionaries

Wikipedia Word definitions in Wikipedia
Keratosis (from keratinocyte , the prominent cell type in the epidermis , and , abnormal) is a growth of keratin on the skin or on mucous membranes . More specifically, it can refer to: actinic keratosis (also known as solar keratosis) hydrocarbon keratosis ...

WordNet Word definitions in WordNet
n. a skin condition marked by an overgrowth of layers of horny skin

Wiktionary Word definitions in Wiktionary
n. (context medicine English) The condition of keratin growing on the skin.

Usage examples of keratosis.

He had never been to the hospital and only once sought medical carefor actinic keratosis, a condition besetting fair-skinned Scandinavians, which had been remedied with the removal of a few frecklelike papules on his forehead and nose, the consequence of too much sun as an adolescent.