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Answer for the clue "Entrance or opening to a hollow organ or tube (especially the vaginal opening) ", 9 letters:
introitus

Word definitions for introitus in dictionaries

WordNet Word definitions in WordNet
n. entrance or opening to a hollow organ or tube (especially the vaginal opening); "the introitus of the vagina"

Wikipedia Word definitions in Wikipedia
An introitus is an entrance that goes into a canal or hollow organ . The vaginal introitus is the opening that leads to the vaginal canal .

Wiktionary Word definitions in Wiktionary
n. (context medicine English) The entrance to a hollow organ or canal; often specifically the entrance to the vagina.

Usage examples of introitus.

Repulsi ab equitatu se in silvas abdiderunt, locum nacti egregie et natura et opere munitum, quem domestici belli, ut videbantur, causa iam ante praeparaverant: nam crebris arboribus succisis omnes introitus erant praeclusi.

In the third the lumen of the vagina, about two inches from the introitus, was distinctly narrowed by a ridge of tissue.