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Answer for the clue "The inability to respond to affective changes in your interpersonal environment ", 15 letters:
insensitiveness

Word definitions for insensitiveness in dictionaries

Wiktionary Word definitions in Wiktionary
n. Quality of being insensitive.

WordNet Word definitions in WordNet
n. the inability to respond to affective changes in your interpersonal environment [syn: insensitivity ] [ant: sensitivity , sensitivity ]