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Answer for the clue "Immunological disorder in which some part of the body's immune system is inadequate and resistance to infectious diseases is reduced ", 16 letters:
immunodeficiency

Word definitions for immunodeficiency in dictionaries

WordNet Word definitions in WordNet
n. immunological disorder in which some part of the body's immune system is inadequate and resistance to infectious diseases is reduced

Douglas Harper's Etymology Dictionary Word definitions in Douglas Harper's Etymology Dictionary
1969, from comb. form of immune + deficiency .

Wiktionary Word definitions in Wiktionary
n. A depletion in the body's natural immune system, or in some component of it.

Wikipedia Word definitions in Wikipedia
Immunodeficiency (or immune deficiency ) is a state in which the immune system 's ability to fight infectious disease is compromised or entirely absent. Most cases of immunodeficiency are acquired ("secondary") due to extrinsic factors that affect the patient's ...

Usage examples of immunodeficiency.

About five thousand types of virus are known, and between them they afflict us with many hundreds of diseases, ranging from the flu and common cold to those that are most invidious to human well-being: smallpox, rabies, yellow fever, ebola, polio, and the human immunodeficiency virus, the source of AIDS.

It is better known as the human immunodeficiency virus, HIV for short, and it is extremely contagious.

With AIDS, you get HIV-Human Immunodeficiency Virus-and then maybe a few years later, it blossoms into full-blown Advanced Immune Deficiency Syndrome, putting the sufferer at risk for contracting fatal cancers or flus.

My crew has to work under very tight restraints, using Class One containment techniques, as with the old immunodeficiency plagues.

The viruses that caused the immunodeficiency plagues are used for gene therapy now.

Monet came into the country in the summer of 1979, around the time that human immunodeficiency virus, or HIV, which causes AIDS, made a final breakout from the rain forest of central Africa and began its long burn through the human race.

In the year 2002, three million people died of AIDS, which is caused by human immunodeficiency virus.

For a disease called severe combined immunodeficiency, SCIDS, the body wasn't producing a protein called adenosine deaminase (ADA).