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Answer for the clue "The act of making immune (especially by inoculation) ", 12 letters:
immunisation

Word definitions for immunisation in dictionaries

WordNet Word definitions in WordNet
n. the act of making immune (especially by inoculation) [syn: immunization ]

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
immunisation \immunisation\ n. Same as immunization . [Chiefly Brit.] Syn: immunization.

Wiktionary Word definitions in Wiktionary
n. (context British immunology English) (alternative spelling of immunization English)