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Answer for the clue "The act of making immune (especially by inoculation) ", 12 letters:
immunisation

Word definitions for immunisation in dictionaries

Wiktionary Word definitions in Wiktionary
n. (context British immunology English) (alternative spelling of immunization English)

WordNet Word definitions in WordNet
n. the act of making immune (especially by inoculation) [syn: immunization ]

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
immunisation \immunisation\ n. Same as immunization . [Chiefly Brit.] Syn: immunization.