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Answer for the clue "Unusual lack of skin color ", 16 letters:
hypopigmentation

Word definitions for hypopigmentation in dictionaries

Wikipedia Word definitions in Wikipedia
Hypopigmentation is the loss of skin color. It is caused by melanocyte or melanin depletion, or a decrease in the amino acid tyrosine , which is used by melanocytes to make melanin.

Wiktionary Word definitions in Wiktionary
n. An abnormally reduced pigmentation

WordNet Word definitions in WordNet
n. unusual lack of skin color [ant: hyperpigmentation ]