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Answer for the clue "Incompetence of the gonads (especially in the male with low testosterone) ", 12 letters:
hypogonadism

Word definitions for hypogonadism in dictionaries

Wiktionary Word definitions in Wiktionary
n. A defect of the reproductive system that results in lack of function of the gonads (ovaries or testes).

Wikipedia Word definitions in Wikipedia
Hypogonadism is a medical term which describes a diminished functional activity of the gonads – the testes and ovaries in males and females, respectively – that may result in diminished sex hormone biosynthesis . In layman's terms, it is sometimes called ...

WordNet Word definitions in WordNet
n. incompetence of the gonads (especially in the male with low testosterone); results in deficient development of secondary sex characteristics and (in prepubertal males) a body with long legs and a short trunk