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Answer for the clue "Incompetence of the gonads (especially in the male with low testosterone) ", 12 letters:
hypogonadism

Word definitions for hypogonadism in dictionaries

Wikipedia Word definitions in Wikipedia
Hypogonadism is a medical term which describes a diminished functional activity of the gonads – the testes and ovaries in males and females, respectively – that may result in diminished sex hormone biosynthesis . In layman's terms, it is sometimes called ...

Wiktionary Word definitions in Wiktionary
n. A defect of the reproductive system that results in lack of function of the gonads (ovaries or testes).

WordNet Word definitions in WordNet
n. incompetence of the gonads (especially in the male with low testosterone); results in deficient development of secondary sex characteristics and (in prepubertal males) a body with long legs and a short trunk