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Answer for the clue "Destruction of tissue by freezing and characterized by tingling, blistering and possibly gangrene ", 9 letters:
frostbite

Alternative clues for the word frostbite

Word definitions for frostbite in dictionaries

Wikipedia Word definitions in Wikipedia
Frostbite is a werewolf novel by David Wellington , published in serial online in July, 2006 and in print in 2009.

Usage examples of frostbite.

Conquistadors were burned by day in the Andean sun, frostbitten by night, malnourished by any good dietary standard, often half-starved for oxygen.

It was the point of triage for all manner of illnesses that rolled down the mountainside to their doorstep: broken bones, pulmonary and cerebral edema, frostbite, heart conditions, dysentery, snow blindness, and all sorts of infections, including STDs.

The temperature at Garbutt Field was one hundred and twelve degrees above zero and they had a cursing gunner with frostbite.

I was exhausted, I was frostbitten, and I found my camp empty except for a semiliterate letter from Berne.

The tips of the green pines, the crests of the silver spruces, waved about masses of vivid gold aspen trees, and wonderful cerise and flaming red of maples, and crags of yellow rock, covered with the bronze of frostbitten sumac.

Apparently Lexie had a slight case of frostbite, and they stayed here an extra day, so she would be in better shape to travel.

Most of all Edwina wanted to see a specialist to make sure that Teddy was alright and Fannie did not lose her frostbitten fingers.

Lenz was diagnosed clinically claustrophobic and took prescription medication for anxiety and ensconcement-phobias, and she ended up successfully filing a Seven-Figure suit against Greyhound Lines and the almost-defunct Commonwealth Highway Authority for psychiatric trauma, public mortification, and second-degree frostbite, and received such a morbidly obese settlement from the Dukakis-appointed 18th-Circus Civil Court that when the check arrived, in an extra-long-size envelope to accommodate all the zeroes, Mrs.

Tranquilino Jeantete had lost one ear tip to frostbite during the same long-ago winter that the Strawberry Mesa Body Shop and Pipe Queen operator, Ruby Archuleta, killed a deer with her bare hands.

Some of the hens had gotten frostbite, for they were tender in those unfeathered fleshy parts, and Crope feared the black rot might set in.

Here, in the camp hospital, he bad the five toes of his right foot amputated, for they were rotten with frostbite he had picked up while wandering through the snow after escaping from the train.

Its only fault was that like so many other sports cars it had a totally inefficient heater, which in spite of coaxing and overhauls stubbornly refused to do more than demist the windscreen and raise my toes one degree above frostbite.

The other patients were, expectably, accident cases or, more numerous, frostbite victims.

He'd passsed out of course with not enough air up there, and he was so frostbit I heard they had to take off one of his feet and all but the thumb on the left hand.

He got his nose frostbit a couple of times trying to track down field mice in winter.