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Answer for the clue "Coarse weedy American perennial herb with large usually perfoliate leaves and purple or dull red flowers ", 9 letters:
feverroot

Word definitions for feverroot in dictionaries

WordNet Word definitions in WordNet
n. coarse weedy American perennial herb with large usually perfoliate leaves and purple or dull red flowers [syn: horse gentian , tinker's root , wild coffee , Triostium perfoliatum ]