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Answer for the clue "An ethical system that evaluates actions by reference to personal well-being through a life based on reason ", 10 letters:
eudemonism

Word definitions for eudemonism in dictionaries

Wiktionary Word definitions in Wiktionary
n. (alternative form of eudaemonism English)

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Eudemonism \Eu*de"mon*ism\, Eudaemonism \Eu*d[ae]"mon*ism\, n. [Gr. ? a thinking happy, fr, ? blessed with a good genius, happy; e'y^ well, good + ? one's demon of genius. See Demon .] That system of ethics which defines and enforces moral obligation ...

WordNet Word definitions in WordNet
n. an ethical system that evaluates actions by reference to personal well-being through a life based on reason [syn: endaemonism ]