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Answer for the clue "A large genus of South American shrubs and small trees of the family Erythroxylaceae ", 12 letters:
erythroxylon

Word definitions for erythroxylon in dictionaries

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Erythroxylon \Er`y*throx"y*lon\, n. [NL., from Gr. 'eryqro`s red + ? wood. So named from the red wood of some species.] (Bot.) A genus of shrubs or small trees of the Flax family, growing in tropical countries. E. Coca is the source of cocaine. See ...

Usage examples of erythroxylon.

AFI were testing mycoherbicides genetically engineered to be plant specific on Cannabis saliva on the coast, and on Erythroxylon coca in the mountains.

There are two varieties in commerce, the Huanuco Coca, or Erythroxylon Coca, which comes from Bolivia and has leaves of a brownish-green colour, oval, entire and glabrous, with a rather bitter taste, and Peruvian Coca, the leaves of which are much smaller and a pale-green colour.