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Answer for the clue "A doctrine of hedonism that was defended by several ancient Greek philosophers ", 12 letters:
epicureanism

Word definitions for epicureanism in dictionaries

Douglas Harper's Etymology Dictionary Word definitions in Douglas Harper's Etymology Dictionary
1751, with reference to the philosophical system of Epicurus; 1847 in a general sense "attachment to or indulgence in luxurious habits," from epicurean + -ism . Earlier was epicurism (1570s).

Wikipedia Word definitions in Wikipedia
Epicureanism is a system of philosophy based upon the teachings of the ancient Greek philosopher Epicurus , founded around 307 BC. Epicurus was an atomic materialist , following in the steps of Democritus . His materialism led him to a general attack on ...

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Epicureanism \Ep`i*cu*re"an*ism\, n. Attachment to the doctrines of Epicurus; the principles or belief of Epicurus.

WordNet Word definitions in WordNet
n. a doctrine of hedonism that was defended by several ancient Greek philosophers

Usage examples of epicureanism.

I adopted Epicureanism and have remained resolutely neutral all my political life.

Cassius had suddenly abrogated Stoicism and espoused Epicureanism, for no reason Servilia could see beyond the fact that it devastated Brutus so much that Brutus was avoiding him.

Blackthorn has taken a sudden interest in Epicureanism, for I shall not believe it.

If this was the sort of pleasurable pursuit advocated by the garden philosophers, no doubt it was perfectly understandable why Epicureanism had seen a revival in the modern century.

His philosophy is a joyous and avid epicureanism that does not deny God but admires Him quite disinterestedly.

Basically, today, we are still caught between the liberal epicureanism of the western democracies, and the radical atheism of the eastern Bolsheviki.