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Answer for the clue "Inflammation of the endocardium and heart valves ", 12 letters:
endocarditis

Word definitions for endocarditis in dictionaries

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Endocarditis \En`do*car*di"tis\, n. [NL. See -itis .] (Med.) Inflammation of the endocardium. [1913 Webster] ||

Wikipedia Word definitions in Wikipedia
Endocarditis is an inflammation of the inner layer of the heart , the endocardium . It usually involves the heart valves . Other structures that may be involved include the interventricular septum , the chordae tendineae , the mural endocardium, or the ...

WordNet Word definitions in WordNet
n. inflammation of the endocardium and heart valves

Wiktionary Word definitions in Wiktionary
n. (context pathology cardiology English) An inflammation of the endocardium and possibly the heart valves.

Usage examples of endocarditis.

She was also suffering from hepatomegaly, uremia, endocarditis, and a host of other serious ailments.

Dead of kidney failure, thrombocytopenia, and endocarditis, toward the end of July, as the cool dawn of another hot blue-gray day broke on the ornamental roof-level brickwork opposite St.