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Answer for the clue "Congenital abnormality involving the absence of some fingers or toes ", 12 letters:
ectrodactyly

Word definitions for ectrodactyly in dictionaries

Wikipedia Word definitions in Wikipedia
Ectrodactyly , split hand , cleft hand , derived from the Greek ektroma (abortion) and daktylos (finger) involves the deficiency or absence of one or more central digits of the hand or foot and is also known as split hand/split foot malformation (SHFM). ...

Wiktionary Word definitions in Wiktionary
n. The deficiency or absence of one or more central digits of the hand or foot.

WordNet Word definitions in WordNet
n. congenital abnormality involving the absence of some fingers or toes