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Answer for the clue "A condition in which an orderly system has been disrupted ", 15 letters:
disorganisation

Word definitions for disorganisation in dictionaries

Wiktionary Word definitions in Wiktionary
n. (alternative spelling of disorganization English)

WordNet Word definitions in WordNet
n. a condition in which an orderly system has been disrupted [syn: disorganization , disarrangement ] the disturbance of a systematic arrangement causing disorder and confusion; "the disorganization of the enemy troops by a flank attack" [syn: disorganization ...

Usage examples of disorganisation.

The fact of the matter is that the autopsical research revealed absolutely nothing but a general disorganisation of the blood-corpuscles, a most peculiar thing, but one the significance of which none of us here can fathom.

And even now, about all we know is that autopsical research reveals absolutely nothing but the general disorganisation of the blood corpuscles.