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Answer for the clue "An antihistamine (trade name Periactin) used to treat some allergic reactions ", 14 letters:
cyproheptadine

Word definitions for cyproheptadine in dictionaries

WordNet Word definitions in WordNet
n. an antihistamine (trade name Periactin) used to treat some allergic reactions [syn: Periactin ]

Wiktionary Word definitions in Wiktionary
n. An antihistaminic, anticholinergic and antiserotonergic agent.

Wikipedia Word definitions in Wikipedia
Cyproheptadine , sold under the brand name Periactin or Peritol , is a first-generation antihistamine with additional anticholinergic , antiserotonergic , and local anesthetic properties.