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Answer for the clue "A developmental abnormality in which there is only one eye ", 8 letters:
cyclopia

Word definitions for cyclopia in dictionaries

Wikipedia Word definitions in Wikipedia
Cyclopia can refer to: Cyclopia , a congenital disorder Cyclopia , a genus of leguminous plants in the subfamily Faboideae

WordNet Word definitions in WordNet
n. a developmental abnormality in which there is only one eye

Wiktionary Word definitions in Wiktionary
n. (context medicine English) A congenital abnormality in which the orbits of the eye do not divide to form separate sockets

Usage examples of cyclopia.

For instance, lithium salts easily induced cyclopia, a single central eye, in fish embryos.