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Answer for the clue "A fungal infection characterized by nodular lesions--first in the lungs and spreading to the nervous system ", 14 letters:
cryptococcosis

Word definitions for cryptococcosis in dictionaries

Wikipedia Word definitions in Wikipedia
Cryptococcosis , also known as cryptococcal disease , is a potentially fatal fungal disease . It is caused by one of two species; Cryptococcus neoformans and Cryptococcus gattii . These were all previously thought to be subspecies of C. neoformans but have ...

WordNet Word definitions in WordNet
n. a fungal infection characterized by nodular lesions--first in the lungs and spreading to the nervous system

Wiktionary Word definitions in Wiktionary
n. (context medicine English) A serious and potentially fatal fungal disease caused by members of the (taxlink Cryptococcus neoformans species noshow=1) species complex, believed to be acquired by inhalation of the infectious propagule from the environment. ...