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Answer for the clue "Destruction of tissue by freezing and characterized by tingling, blistering and possibly gangrene ", 9 letters:
cryopathy

Word definitions for cryopathy in dictionaries

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
cryopathy \cryopathy\ n. destruction of tissue by freezing and characterized by tingling, blistering and possibly gangrene. Syn: frostbite.

WordNet Word definitions in WordNet
n. destruction of tissue by freezing and characterized by tingling, blistering and possibly gangrene [syn: frostbite ]