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Answer for the clue "(medicine) a reason that makes it inadvisable to prescribe a particular drug or employ a particular procedure or treatment ", 16 letters:
contraindication

Word definitions for contraindication in dictionaries

Longman Dictionary of Contemporary English Word definitions in Longman Dictionary of Contemporary English
noun EXAMPLES FROM CORPUS ▪ Age is not an absolute contraindication , although there are obvious constraints in elderly patients. ▪ Even patients with diabetes mellitus complicated by autonomic neuropathy are not necessarily a contraindication to restorative ...

Wiktionary Word definitions in Wiktionary
n. (context medicine English) A factor or symptom which makes the prescribed treatment inadvisable.

WordNet Word definitions in WordNet
n. (medicine) a reason that makes it inadvisable to prescribe a particular drug or employ a particular procedure or treatment [ant: indication ]

Wikipedia Word definitions in Wikipedia
In medicine , a contraindication is a condition or factor that serves as a reason to withhold a certain medical treatment due to the harm that it would cause the patient. Contraindication is the opposite of indication , which is a reason to use a certain ...

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Contraindication \Con"tra*in`di*ca"tion\, n. (med.) An indication or symptom which forbids the method of treatment usual in such cases.

Usage examples of contraindication.

Surgery can, of course, change some of these parts but there may be serious contraindications to surgery besides cost.

Sorenson of the department of immunology does not think the AIDS is an absolute contraindication for surgery at this time.

If there were no contraindications, he liked balanced anesthesia the best, meaning he did not have to give the patient some gargantuan dose of any one agent, but rather he balanced the needs by a number of different agents.