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Answer for the clue "A congenital defect in which one or more toes or fingers are abnormally positioned ", 12 letters:
clinodactyly

Word definitions for clinodactyly in dictionaries

Wikipedia Word definitions in Wikipedia
Clinodactyly (from the Ancient Greek κλίνειν meaning "to bend" and δάκτυλος meaning "digit") is a medical term describing the curvature of a digit (a finger or toe) in the plane of the palm, most commonly the fifth finger (the " little finger ") towards ...

WordNet Word definitions in WordNet
n. a congenital defect in which one or more toes or fingers are abnormally positioned