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Answer for the clue "A specialized condensed region of a chromosomes that appears during mitosis where the chromatids are held together to form an X shape ", 10 letters:
centromere

Word definitions for centromere in dictionaries

Wiktionary Word definitions in Wiktionary
n. (context genetics English) The central region of a eukaryotic chromosome where the kinetochore is assembled.

Wikipedia Word definitions in Wikipedia
The centromere is the part of a chromosome that links sister chromatids or a dyad. During mitosis , spindle fibers attach to the centromere via the kinetochore . Centromeres were first thought to be genetic loci that direct the behavior of chromosomes. ...

WordNet Word definitions in WordNet
n. a specialized condensed region of each chromosome that appears during mitosis where the chromatids are held together to form an X shape; "the centromere is difficult to sequence" [syn: kinetochore ]

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
centromere \centromere\ n. (Biol.) a specialized condensed region of a chromosomes that appears during mitosis where the chromatids are held together to form an X shape.

Usage examples of centromere.

It needs something called a centromere, which is crucial during cell division.

The whole process of cell division, including the details of the centromere, remains mysterious.