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Answer for the clue "The act of coagulating blood and destroying tissue with a hot iron or caustic agent or by freezing ", 13 letters:
cauterisation

Word definitions for cauterisation in dictionaries

WordNet Word definitions in WordNet
n. the act of coagulating blood and destroying tissue with a hot iron or caustic agent or by freezing [syn: cautery , cauterization ]

Usage examples of cauterisation.

From the several foregoing facts, there can be no doubt that the cauterisation of the tip of the radicle of this Cucurbita on one side, if done lightly enough, causes the whole growing part to bend to the opposite side.

Therefore a slight cauterisation of the tip checks slightly the growth of the whole radicle, and manifestly stops the bending of that part which ought to bend most under the influence of geotropism, and which still continues to increase greatly in length.