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Answer for the clue "A disorder (usually of unknown origin) of the heart muscle (myocardium) ", 14 letters:
cardiomyopathy

Word definitions for cardiomyopathy in dictionaries

Wiktionary Word definitions in Wiktionary
n. (context pathology English) The deterioration of the myocardium.

Wikipedia Word definitions in Wikipedia
Cardiomyopathy (literally "heart muscle disease") is the measurable deterioration for any reason of the ability of the myocardium (the heart muscle) to contract, usually leading to heart failure . Common symptoms include dyspnea (shortness of breath) and ...

WordNet Word definitions in WordNet
n. a disorder (usually of unknown origin) of the heart muscle (myocardium) [syn: myocardiopathy ]