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Answer for the clue "Perennial vine of dry parts of central and southwestern United States and Mexico having small hard mottled green inedible fruit ", 11 letters:
calabazilla

Word definitions for calabazilla in dictionaries

WordNet Word definitions in WordNet
n. perennial vine of dry parts of central and southwestern United States and Mexico having small hard mottled green inedible fruit [syn: prairie gourd , prairie gourd vine , Missouri gourd , wild pumpkin , buffalo gourd , Cucurbita foetidissima ]