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Answer for the clue "Inability to produce hybrids that are both viable and fertile ", 11 letters:
cacogenesis

Word definitions for cacogenesis in dictionaries

Wiktionary Word definitions in Wiktionary
n. (context medicine English) A morbid, monstrous, or pathological growth or product; an abnormality in structure; a monstrosity.

WordNet Word definitions in WordNet
n : inability to produce hybrids that are both viable and fertile