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Answer for the clue "Any general reduction in vitality and strength of body and mind resulting from a debilitating chronic disease ", 7 letters:
cachexy

Word definitions for cachexy in dictionaries

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Cachexia \Ca*chex"i*a\, Cachexy \Ca*chex"y\, n. [L. cachexia, Gr. kachexi`a; kako`s bad + "e`xis condition.] A condition of ill health and impairment of nutrition due to impoverishment of the blood, esp. when caused by a specific morbid process (as cancer ...

Wiktionary Word definitions in Wiktionary
n. (context medicine archaic English) cachexia.

WordNet Word definitions in WordNet
n : any general reduction in vitality and strength of body and mind resulting from a debilitating chronic disease [syn: cachexia , wasting ]

Usage examples of cachexy.

That is to say except in a very few cases of vicious cachexy, where it was only done to please the relations.