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Answer for the clue "Any physiologically active internal secretion especially one of uncertain classification ", 8 letters:
autocoid

Word definitions for autocoid in dictionaries

WordNet Word definitions in WordNet
n. any physiologically active internal secretion especially one of uncertain classification [syn: autacoid ]

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
autocoid \autocoid\ n. 1. any physiologically active internal secretion, especially one of uncertain classification. Syn: autacoid.

Wiktionary Word definitions in Wiktionary
n. (alternative form of autacoid English)

Usage examples of autocoid.

It affects individual neurons but also whole networks of cells as if it were an autocoid or brain hormone.