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Answer for the clue "A tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem ", 10 letters:
asthenopia

Word definitions for asthenopia in dictionaries

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Asthenopia \As`the*no"pi*a\, n. [Gr. 'a priv. + sqe`nos strength + 'w`ps eye.] Weakness of sight. --Quain. -- As`the*nop"ic , a.

WordNet Word definitions in WordNet
n. a tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem [syn: eyestrain ]

Wiktionary Word definitions in Wiktionary
n. An ophthalmological condition that manifests itself through nonspecific symptoms such as fatigue, red eyes, eye strain, pain in or around the eyes, blurred vision, headache and occasional double vision.