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Answer for the clue "Used as a calorie-free sweetener ", 9 letters:
aspartame

Alternative clues for the word aspartame

Word definitions for aspartame in dictionaries

Douglas Harper's Etymology Dictionary Word definitions in Douglas Harper's Etymology Dictionary
commercial name of an artificial sweetener, 1973, from aspartic acid (1836), formed irregularly from asparagine (1813), a compound found in asparagus, beet-root, etc., which was named from asparagus + chemical suffix -ine (2). The reason for -ame is unknown. ...

Wikipedia Word definitions in Wikipedia
Aspartame ( APM ; or ) is an artificial, non- saccharide sweetener used as a sugar substitute in some foods and beverages. In the European Union, it is codified as E951 . Aspartame is a methyl ester of the aspartic acid / phenylalanine dipeptide . It was ...

Usage examples of aspartame.

A study of hyperactive children at the University of Toronto found that they reacted the same to sucrose, aspartame, and saccharin.

Also, Splenda stands up to heat, unlike aspartame, which means you can use it in baked goods.

Pearl, unpack and hang everything up carefully, iron things that had wrinkled, take a bath, put on the pajamas she usually wore when she slept without me, get in bed with Pearl, have a half cup of frozen chocolate yogurt sweetened with aspartame, and watch a movie.

I downed both Diet Cokes along the way, but all the time kept a finger on the pull-tab of my aspartame grenade.