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Answer for the clue "A medicine that inhibits cholinesterase by combining with it and so has a cholinergic effect ", 18 letters:
anticholinesterase

Word definitions for anticholinesterase in dictionaries

Wiktionary Word definitions in Wiktionary
n. Any agent that inhibits the activity of cholinesterase

WordNet Word definitions in WordNet
n. a medicine that inhibits cholinesterase by combining with it and so has a cholinergic effect

Usage examples of anticholinesterase.

Twenty-five-millimeter cartridge, filled with a half a milliliter of Novichok, a V-class anticholinesterase agent that will paralyze you in about eight seconds.

The fact that they are anticholinesterase agents is what makes ophosphates so dangerous.