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Answer for the clue "An acute blood disorder (often caused by radiation or drug therapy) characterized by severe reduction in granulocytes ", 15 letters:
agranulocytosis

Word definitions for agranulocytosis in dictionaries

Wiktionary Word definitions in Wiktionary
n. (context disease English) An acute condition involving a severe and dangerous leukopenia, particularly of neutrophils, causing a neutropenia in the circulating blood.

WordNet Word definitions in WordNet
n. an acute blood disorder (often caused by radiation or drug therapy) characterized by severe reduction in granulocytes [syn: agranulosis , granulocytopenia ]

Wikipedia Word definitions in Wikipedia
Agranulocytosis , also known as agranulosis or granulopenia , is an acute condition involving a severe and dangerous leukopenia (lowered white blood cell count), most commonly of neutrophils causing a neutropenia in the circulating blood. It is a severe ...

Usage examples of agranulocytosis.

Maybe because it causes agranulocytosis, tachycardia, and seizure in most patients.

It was like a case we had three months ago, a rare thing called agranulocytosis, the complete absence of white cells in the blood.

I need to know whether this hospital has had an unusual cluster of cases of agranulocytosis and whether that cluster has ceased as mysteriously as it appeared.

Just as with agranulocytosis there were many causes of haemolytic anaemia.